KARYNG Retinol Renewing Serum 30ml/1 fl oz Dr. Karyn Grossman *New In Box*. Apply PM. Pump a small amount onto fingertips and smooth onto face prior to applying Restructuring Night Cream. Start every other PM and increase to nightly as tolerated. Use SPF30+ containing product while using retinol and avoid sun exposure. Avoid use on inflamed or irritated skin