Pure Bee Venom Apitoxin. As used in skincare to reduce wrinkles effectively. Very Potent. Simply add a small amount of water and add to your favorite moisturizer. Commercial bee venom creams have very little actual Bee Venom (0.01%). The suggested recommendation is 0.5% of total weight of the contents of your cream or serum and 10% for compound cream as used for pain relief. Harvested April 2023. Expires in 2 years when left in a cool environment. 500mg Bee Venom is equivalent to 1,700 live bee stings and should be used with 3.5 oz. of cream OR 100mL of serum ***NOT intended for internal use*** ***Item is not FDA-approved*** MADE IN USA